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☆ Viking Therapeutics emerges as a strong weight loss drug player — or takeover target
▼ + stars: | 2024-03-03 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +8 min

In this article VKTX Follow your favorite stocks CREATE FREE ACCOUNTCr | Istock | Getty ImagesBiotech company Viking Therapeutics has emerged as a strong potential entrant — or takeover target — in the budding weight loss drug market. Their treatments sparked the weight loss drug industry gold rush over the past year despite their hefty price tags and barriers to insurance coverage. It's too early to say whether Viking's drug could have an edge over existing or developing weight loss treatments. The pharmaceutical giant could also launch a slate of other weight loss treatments over the next few years that may have advantages over Zepbound, whether they offer more weight loss or convenience. That could give Viking the commercial and manufacturing capabilities needed to compete in the weight loss drug market.

Persons: Eli Lilly, Eli Lilly's Zepbound, Viking, Goldman Sachs, Eli Lilly’s, Brendan Mcdermid, GLP, Brian Lian, William Blair, Andy Hsieh, Hsieh, Eli Lilly's, Jefferies, Akash Tewari, doesn't, Mike Segar, Lian, William Blair's Hsieh, Oppenheimer, Jay Olson Organizations: Getty Images Biotech, Viking Therapeutics, Novo Nordisk, Reuters, Viking, Novo, U.S . Food, Drug Administration, Company, Deutsche Bank, CNBC Locations: New York City, Branchburg , New Jersey

"After these results, it looks like there is no stopping Modi," said Yashwant Deshmukh, poll expert with C-Voter agency, adding that stopping Modi would be a "herculean task". The BJP won the regional votes in three of four major states, including central Rajasthan and Chhattisgarh which were ruled by Congress. One of the challenges facing the opposition are the factious ties within the INDIA alliance. Congress refused to share seats in state polls with key regional ally the Samajwadi Party. "The future of the alliance is good if the Congress party works on it with full commitment," he said.

Persons: India's, Narendra Modi, of Home Affairs Amit Shah, Narendra Modi's, Modi, Yashwant Deshmukh, Rahul Gandhi, Manish Tewari, Manoj Kaka, Gandhi, Baijayant Panda, Saurabh Sharma, Miral Organizations: Bharatiya Janata Party, BJP, Indian, Union, of Home Affairs, Narendra Modi's Bharatiya Janata Party, Voter, Congress, Reuters, Samajwadi Party, Thomson Locations: Ahmedabad, India, DELHI, Britain, Rajasthan, Chhattisgarh, Karnataka, INDIA, Lucknow

New Delhi CNN —Qatar has sentenced eight Indian nationals to death, India’s government said, following their reported detention in Doha last year on espionage charges. In a statement Thursday, India’s Ministry of External Affairs said it was “deeply shocked” by the verdict and would take up the matter with Qatari authorities. “We are in touch with the family members and the legal team, and we are exploring all legal options,” the statement said. CNN has reached out to Qatar’s government but has not received an official comment. The eight Indians were detained by Qatari authorities on spying charges on August 2022, CNN affiliate CNN-News18 reported Thursday.

Persons: India’s, “, Manish Tewari, Tewari, Satbir Singh, ”, Singh, Narendra Modi, ” Singh, Al Dahra, News18 Organizations: New, New Delhi CNN, Qatar, India’s Ministry, External Affairs, CNN, Indian Navy, Affairs, Indian Ex, Servicemen, Qatar Naval, United Nations Locations: New Delhi, Doha, Indian, Qatar

☆ Pfizer gets upgrade at Jefferies, which says there's a buying opportunity in the pharma giant's stock
▼ + stars: | 2023-10-16 | by ( Brian Evans | ) www.cnbc.com time to read: +1 min

Jefferies thinks its time for investors to go long on Pfizer . "In our view, PFE has one of the most intriguing catalyst paths over the next yr in large cap pharma and trades ~15% below where it traded at the start of the COVID pandemic." The analyst added Pfizer has already presented "an impressive innovation framework" that has helped the company adapt to healthcare headwinds, which underpinned the bullish long-term view. "During the pandemic, Pfizer in collaboration with Biontech rolled out COVID vaccines in a historical timeframe. PFE YTD mountain Pfizer stock YTD — CNBC's Michael Bloom contributed to this report.

Persons: Jefferies, Akash Tewari, it's, Tewari, PFE, Biontech, Paxlovid, Michael Bloom Organizations: Pfizer, pharma

☆ Shares of dialysis providers drop after Ozempic's early kidney trial success
▼ + stars: | 2023-10-11 | by ( ) www.reuters.com time to read: +2 min

The outdoor sign seen at the DaVita Dialysis clinic in Denver February 16, 2016. U.S.-listed shares of Fresenius fell 16.4%, to $17.5, and Davita fell about 16%, to $76.7, in premarket hours. Shares of U.S.-based Baxter International (BAX.N), which makes products used by dialysis therapy providers, also fell about 9%, to $33.99 premarket. Davita and U.S.-listed shares of Fresenius Medical are among the top percentage losers on the New York Stock Exchange. As of Tuesday's close, U.S.-listed shares of Fresenius were up about 28.2%, Davita's shares were up 22.2%, while Baxter's shares were down about 27% so far this year.

Persons: Rick Wilking, Ozempic, Danish drugmaker, Veronika Dubajova, Davita, Eli Lilly's, Akash Tewari, Fresenius, Mariam Sunny, Janane Venkatraman, Pooja Desai Organizations: REUTERS, Novo Nordisk's, Citi, Baxter, Jefferies, Fresenius, New York Stock Exchange ., Thomson Locations: Denver, Danish, Fresenius, New York Stock Exchange . Frankfurt, U.S, Bengaluru

☆ Acelyrin's skin disease drug trial failure wipes off IPO gains
▼ + stars: | 2023-09-12 | by ( Christy Santhosh | ) www.reuters.com time to read: +2 min

Sept 12 (Reuters) - Shares of drug developer Acelyrin (SLRN.O) on Tuesday erased all gains made since their stellar market debut in May, as the company's experimental lead drug failed to show superiority to placebo in reducing symptoms of an inflammatory skin disease. HS is a chronic inflammatory skin condition that causes painful lumps under the skin. Acelyrin said the trial was hit by early discontinuations as well as better placebo efficacy rates. However, Jefferies analyst Akash Tewari slashed the price target on Acelyrin's stock to $15 from $31, calling the latest data "painfully disappointing." "It's difficult to glean much from the data given how poorly the trial was run.

Persons: Acelyrin, Acelyrin's izokibep, Hidradenitis, Piper Sandler, Jefferies, Akash Tewari, We'll, Christy Santhosh, Saumyadeb Chakrabarty Organizations: Ventyx Biosciences, Apogee Therapeutics, Thomson Locations: Acelyrin, Bengaluru

☆ Jefferies upgrades Eli Lilly as enthusiasm around weight-loss drugs grows following Wegovy study
▼ + stars: | 2023-08-09 | by ( Brian Evans | ) www.cnbc.com time to read: +2 min

Jefferies is encouraged by recent results from a weight-loss drug study that could help lift Eli Lilly . Analyst Akash Tewari lauded the strong results from a recent trial study surrounding Novo Nordisk's weight loss drug Wegovy . Eli Lilly also raised its full-year guidance on Tuesday. Eli Lilly as added more than 42% upside from the start of the year. LLY YTD mountain Eli Lilly year to date — CNBC's Michael Bloom contributed to this report.

Persons: Jefferies, Eli Lilly, Akash Tewari, Wegovy, Tewari, Eli Lilly's, NVO, Michael Bloom

☆ Why this landmark cardiac study means a bigger market for Lilly's blockbuster weight loss drug
▼ + stars: | 2023-08-09 | by ( Christina Cheddar Berk | ) www.cnbc.com time to read: +7 min

A landmark study of the cardiovascular benefits of weight loss drug Wegovy is being seen as a pivotal step toward broadening access to these drugs. The drug, also known as tirzepatide, is expected to be approved for weight loss by the Food and Drug Administration by year-end. Notably, Medicare does reimburse obese patients for weight loss surgery, but Mounjaro has been able to help patients realize an average weight loss that approaches the typical success of bariatric procedures. If CMS is able to reimburse patients for weight loss treatment that would significantly increase access, boosting sales. "This is the first time a weight [loss] medicinal intervention has shown to have cardiovascular risk reduction.

Persons: enrollees, Eli Lilly, Lilly, Akash Tewari, NVO, Tewari, Wells, Mounjaro, Mohit Bansal, Robert Califf, Goldman Sachs, Chris Shibutani, Shibutani, Goldman, Refinitiv, Morgan Stanley, comorbidities, Bansal Organizations: Nordisk's Ozempic, Centers for Disease Control, Food and Drug Administration, Jefferies, Medicare, Services, GLP, STAT, Goldman, Lilly, Novo Nordisk, BMI, Novo Locations: U.S, GLP, Tuesday's

☆ A research page about a new AI image tool that's basically Photoshop on steroids is so popular the website is crashing
▼ + stars: | 2023-05-19 | by ( Sindhu Sundar | ) www.businessinsider.com time to read: +2 min

A new AI tool, part of a research effort, could allow users to quickly edit and morph photos. The tool would let users quickly adjust the positions, stances, expressions and sizes of photo subjects. The research page showing demos of the tool has been crashing due to interest, The Verge reported. A page by the researchers showing video demos of the tool is already crashing as aspiring users flock to the site, The Verge reported. The tool could be the latest in an array of AI tools being opened up to the public, like OpenAI's DALL-E image generation tool, and many others.

☆ Eli Lilly says experimental Alzheimer's drug reduces brain plaque in early study
▼ + stars: | 2023-04-05 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +4 min

Eli Lilly 's experimental Alzheimer's drug lowered levels of brain plaque in patients who are in the earliest stages of the devastating disease, initial data shows. Researchers have argued that accumulation of amyloid plaque is a crucial first step toward the cognitive decline observed in Alzheimer's disease. The early data comes as Eli Lilly continues its decades-long bid to bring an Alzheimer's drug to the market. Eli Lilly found the drug caused a "rapid and robust" clearance of amyloid plaque, the presentation said. But Tewari said it's unclear if clearing amyloid plaque will lead to clinical benefits like a reduction in cognitive decline.

☆ Jefferies says Regeneron's Dupixent drug could drive shares 15% higher
▼ + stars: | 2023-03-24 | by ( Samantha Subin | ) www.cnbc.com time to read: +1 min

Regeneron 's Dupixent drug could serve as the next big catalyst for shares of the pharmaceutical company, according to Jefferies. REGN YTD mountain Regeneron shares so far this year A study released Thursday indicated that Dupixent, created with Sanofi, showed promise as a treatment for patients with COPD. Broken down, the data showed Dupixent reduced some moderate or severe acute exacerbations of COPD by 30%, compared with a placebo over a 52-week period. Tewari also views Eylea as another upside driver for shares as Wall Street gains more clarity on the drug. Shares of Regeneron have been on a tear in 2023, up 11% after gaining 14% during 2022's market rout.

☆ This week's best performers include Regeneron and these two solar stocks
▼ + stars: | 2023-03-24 | by ( Alex Harring | ) www.cnbc.com time to read: +5 min

Solar stocks Enphase and SolarEdge were also among the best performing stocks as investors continued weighing how the Inflation Reduction Act could boost solar companies. The average price target on the stock implies upside of 49.3% over the next 12 months. The stock's average price target implies it could rally 29.5%. Around three-fifths of analysts rate the stock a buy with a price target that implies a potential 16.7% rally. Technology stocks made up the majority of the list this week as investors bet growth stocks could benefit in an environment with lower interest rates.

☆ Here's why more than 60% of Fortune 500 companies are incorporated in Delaware
▼ + stars: | 2023-03-13 | by ( Charlotte Morabito | In Charlottemorabito | ) www.cnbc.com time to read: +2 min

But it's home to more than 60% of Fortune 500 companies, the state says, including Google parent company Alphabet, Amazon, CVS Health, and CNBC parent company Comcast. One of Delaware's major advantages is its Court of Chancery, which is a separate court system specifically for handling corporate cases. "It's a misnomer that Delaware is a tax haven for corporations," said Gigi Tewari, assistant professor at Widener University Delaware Law School. "So many people believe that, I should incorporate my business in Delaware because I'm going to save so much on corporate tax. Actually, Delaware is on the higher end for corporate tax."

☆ Indian police are looking into the death of a Russian sausage magnate critical of Putin's war in Ukraine, who died after an alcohol-fueled trip in the jungle
▼ + stars: | 2023-01-25 | by ( Azmi Haroun | ) www.businessinsider.com time to read: +4 min

Russian sausage magnate Pavel Antov died in India in late December and was a longtime Putin ally. According to The Wall Street Journal, Indian police have discovered new details about the pair of deaths in late December. Russian lawmaker Pavel Antov died in Rayagada, India, two days after his friend, Vladimir Bydanov. Bydanov, who shared a room with Antov, died of a heart attack on Antov's birthday. Antov is at least the 19th Russian executive who has mysteriously perished throughout the course of the war, according to The Journal.

More men are being diagnosed with advanced prostate cancer that is less likely to respond to treatments, a new study from the American Cancer Society suggests. Even more concerning than the rise in advanced cancer diagnoses is the increased number of prostate cancer deaths. “This increase is concerning and requires a new look at prostate cancer screening,” Tewari said. Essentially, that’s like 16 Boeing 747s crashing.”Black men had a 70% higher incidence of prostate cancer than white men. Declines in prostate cancer screeningIn 1994, the Food and Drug Administration approved the use of measurements of the prostate specific antigen (PSA) to be used as part of a screening test for prostate cancer.

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